
Study suggests a new way to develop intra-tumor immunotherapies to fight head and neck cancer
2023-03-14
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Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health have identified a strong association between the product of a gene expressed in most cancers, including the most common type of head and neck cancer, and elevated levels of white blood…

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia
2023-03-14
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Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically target AML cells are lacking, which would permit the immune system to attack cancer. Two research teams of…

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells
2023-03-13
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A new review paper titled “Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells” has been published in Oncotarget. Cancer therapy is limited by toxicity in normal cells and drug-resistance in cancer cells. In his latest review, Mikhail V. Blagosklonny, M.D., Ph.D., from Roswell Park Comprehensive Cancer…

Scientists reveal how XBP1s interacts with IL-15 to enhance the survival of natural killer cells
2023-03-13
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A new study published in Science Immunology points to a promising therapeutic approach for future cancer treatments based on natural killer cells (NK), which are immune cells that bind to tumor cells and destroy them. City of Hope scientists created a knockout mouse model for a protein called XBP1s to…

Pediatric invasive group A streptococcus infections on the rise
2023-03-13
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From October to December 2022, a resurgence of pediatric invasive Group A Streptococcus (iGAS) infections occurred, with most cases occurring among those without underlying medical conditions, according to research published in the March 10 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. Meghan…

Ask the Pediatrician: How do I prevent dehydration when my child is vomiting?
2023-03-13
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What causes vomiting? Urinating less frequently (for infants, fewer than six wet diapers daily) Dry tongue and inside of mouth Dry eyes and fewer tears when crying Excessive sleepiness or fussiness Wrinkled skin In babies, a sunken “soft spot” on their head In older children, weakness or dizziness when trying…