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A research team assessed the safety of conditionally immortalized proximal tubule epithelial cells for bioartificial kidney application, by using in vitro assays and athymic nude rats. They demonstrate that these cells do not possess key properties of oncogenically transformed cells, including anchorage-independent growth, lack of contact inhibition and apoptosis-resistance. Taken…
Opioids play an important role in how cancer patients manage pain, but the ongoing opioid epidemic has raised concerns about their potential for abuse. Pain remains one of the most difficult symptoms associated with cancer. More than half of cancer patients undergoing treatment experience moderate to severe pain. Despite the…
Adults with type 2 diabetes may have more to gain by participating in physical activity and exercise than healthy adults, but they may also have more to lose, according to University of Alberta exercise and diabetes physiology researchers. “Exercise can improve one’s glucose levels, which can help slow the progression…
Scientists have peered inside the brain to show how taking DMT affects human consciousness by significantly altering the brain’s electrical activity. DMT (or dimethyltryptamine) is one of the main psychoactive constituents in ayahuasca, the psychedelic brew traditionally made from vines and leaves of the Amazon rainforest. The drink is typically…
Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a combination of two anti-cancer compounds that shrank pancreatic tumors in mice—supporting the immediate evaluation of the drugs in a clinical trial. U.S. Food and Drug Administration (FDA)-approved versions of the compounds are used today to treat certain leukemias and…
Nearly half of Americans in their 50s and early 60s think they’re likely to develop dementia as they grow older, but only 5% of them have actually talked with a doctor about what they could do to reduce their risk, a new study finds. Meanwhile, a third or more say…
