A virological study of the first German Covid-19-patients, published in the journal Nature, shows that Infected even in case of mild symptoms and the beginning of the disease, high amounts of the novel Coronavirus.
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For the study, nine patients were of the so-called Munich group, the first related COVID-19-cases in Germany, in Munich, clinic Schwabing, medical care. The Patients were young to middle-aged woman, and in spite of the milder symptoms a stationary been recorded. They suffered, especially if they have cough and fever, as well as an impaired smell and taste sensation. The clinic staff took several times a day samples from throat, lung, blood, stool and urine.
As the researchers led by Professor Dr. Clemens Wendtner, chief physician at the Munich hospital Munich-Schwabing, and the Berlin-based virologist Professor Dr. Christian Drosten was able to observe, the virus excretion in the throat of the Covid-19-Patients in the first week after the onset of symptoms is very high. Also in the cough-expectoration of large quantities of Virus could be detected-genetic make-up. Both the throat swab and the cough expectoration were infectious Virus particle isolate. "This means that the new Coronavirus can not only in the lungs, but in the throat multiply and thus very easily transferable ist", declares Drosten.
Contagious before symptoms spürbar are
In most cases, the viral load decreased in the throat on the first week of illness significantly. The virus excretion in the lungs also fell, but later than in the throat. "The high viral load in the throat is equal to the onset of symptoms suggests that Covid-19-Diseased at a very early stage are infectious, possibly even before you notice that you are sick sind", Colonel doctor explains private lecturer Dr. Roman Wölfel, one of the first authors of the study.
The researchers also were able to show increases SARS-CoV-2 probably also in the gastro-intestinal tract. However, it was in the stool of patients, no infectious virus detected. In blood and urine, the Virus is not found.