Brodalumab Shows Promise in Axial Spondyloarthritis

NEW YORK (Reuters Health) – Brodalumab may be a potential therapeutic option for patients with axial spondyloarthritis (axSpA), according to interim results of a phase-3 study. Brodalumab, which selectively inhibits interleukin-17 receptor A (IL-17RA), is approved for the treatment of plaque psoriasis in North America, Canada, Europe, Japan and other…

COVID-19 Vaccination Strategies Suggested for Patients on Antirheumatic Immunosuppressive Therapy

NEW YORK (Reuters Health) – UK experts propose evidence-based management strategies for rheumatology patients on immunosuppressive therapy, including delaying/postponing rituximab, as appropriate. “The aim of this viewpoint article is to outline the existing data on the effect of antirheumatic therapy on vaccine responses in patients with inflammatory arthritis, and to…

Can Supplementary Estrogen Relieve MS Symptoms?

It’s time for a large-scale phase 2 study into whether supplementary estrogen can relieve multiple sclerosis (MS) symptoms in menopausal women with the disease, a neurologist told colleagues at the meeting held by the Americas Committee for Treatment and Research in Multiple Sclerosis. This kind of research should explore the…

Psoriasis Pathophysiology Insights Carry Treatment Implications

Dr Kenneth Brian Gordon Several surprising recent insights into the pathophysiology of psoriasis may eventually lead to superior treatment strategies for this common T-cell-mediated disease, Kenneth Brian Gordon, MD, said at MedscapeLive’s annual Las Vegas Dermatology Seminar, held virtually. Among these unexpected developments was the startling finding that skin inflammation in…

Why COVID-19 May Be More Deadly Than Flu, Other Coronaviruses

Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Although cytokine storms are not unique to COVID-19, they are triggered in an unusual way that makes them potentially more severe and deadly compared with those triggered by influenza or other coronaviruses, new evidence reveals. Important differences in the…

COVID-19 Vaccination Recommended for Rheumatology Patients

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. People with rheumatic diseases should get vaccinated against SARS-CoV-2 as soon as possible, the American College of Rheumatology (ACR) recommends. “It may be that people with rheumatic diseases are at increased risk of developing COVID or…