Breaking the ‘stalemate’ in the most common soft tissue sarcoma in children: First randomized clinical trial to show positive results in rhabdomyosarcoma since 1974

A phase 2 clinical trial has found that combining a molecular targeted drug called temsirolimus with chemotherapy shows promise in the treatment of rhabdomyosarcoma, the most common soft tissue sarcoma in childhood. The Children’s Oncology Group trial was led by Leo Mascarenhas, MD, MS, Deputy Director of the Children’s Center…

AI reveals new breast cancer types that respond differently to treatment: Revelations could personalize treatment, including picking out those likely to benefit from immunotherapy

Scientists have used artificial intelligence to recognise patterns in breast cancer — and uncovered five new types of the disease each matched to different personalised treatments. Their study applied AI and machine learning to gene sequences and molecular data from breast tumours, to reveal crucial differences among cancers that had…