Nerve cell protection free from side effects

The hormone erythropoietin (Epo) is a well-known doping substance that has a long history of abuse in endurance sports such as cycling. In addition to promoting red blood cell production (erythropoiesis), which improves the oxygen supply, Epo also protects nerve cells from cell death. In order to use this effect…

Boy with genetic condition needs a stem cell match

Parents in desperate search for a stem cell donor to help their five-month-old son beat a rare illness ‘which doctors thought was cancer’ Daniel McAvoy, of Huntington in Cambridgeshire, has Wiskott-Aldrich syndrome The crippling condition is thought to strike as little as one in a million children  Daniel spent 11 days…

Giant cell arteritis occurs at similar rate in blacks, whites

(HealthDay)—Biopsy-proven giant cell arteritis (BP-GCA) occurs at a similar rate among white and black patients, according to a study published online Aug. 8 in JAMA Ophthalmology. Anna M. Gruener, B.M.B.S., from the Johns Hopkins Wilmer Eye Institute in Baltimore, and colleagues conducted a retrospective cohort study involving all 586 patients…

Mechanical forces control cell fate during brain formation

A new study coordinated by the Research Group in Developmental Biology at UPF shows that during the embryonic development of the brain, the cells that are between adjacent segments detect the mechanical forces generated during morphogenesis to regulate the balance between progenitor stem cells and differentiated neurons. The study has…

Voxelotor improves hemoglobin levels in sickle cell disease

(HealthDay)—For individuals with sickle cell disease, 1,500 mg of voxelotor increases hemoglobin levels and reduces the incidence of worsening anemia compared with placebo, according to a study published in the June 14 issue of the New England Journal of Medicine. Elliott Vichinsky, M.D., from the University of California at San…