Emotional aspects of chronic pain isolated in brain circuitry

Negative emotional states and physical pain are intimately connected. Numerous people who suffer from chronic, persistent pain also deal with negative emotions and loss of motivation. Some even become clinically depressed eventually, and doctors sometimes prescribe antidepressants to treat chronic pain, even though the pathways that link pain and mood…

App Scans Medical Records to Find Those With Kidney Disease

Researchers have validated a software algorithm that can automatically scan through electronic medical records to identify people with chronic kidney disease (CKD) and classify them by CKD severity stage. In a pair of validation studies the algorithm had a positive predictive value for identifying CKD of 95%-97%, and a negative…

Entresto Granted Expanded Indication in Chronic Heart Failure by FDA

EAST HANOVER, N.J., Feb. 16, 2021 — Novartis today announced that the US Food and Drug Administration (FDA) has approved the following expanded indication for Entresto® (sacubitril/valsartan): to reduce the risk of cardiovascular death and hospitalization for heart failure in adult patients with chronic heart failure.1 Benefits are most clearly evident in patients with left ventricular…