New insights into the control of inflammation

Scientists at The Wistar Institute discovered that Early Growth Response 1 (EGR1), a protein that turns on and off specific genes during blood cell development, inhibits expression of pro-inflammatory genes in macrophages. As part of their function to protect the body against pathogens, macrophages play a major role in initiation,…

Predicting poor pain control following elective spine surgery

Researchers at the University of Calgary have developed and validated a clinical prediction scale that can be used to determine which patients are more likely to experience inadequate pain control following elective spine surgery. Armed with this knowledge, spine surgeons can ensure that patients obtain appropriate patient education and individualized…

Birth control pill could cut women’s risk for asthma

(HealthDay)—Could birth control pills build a bulwark against asthma? New research suggests that hormonal contraceptives, which alter the natural ebb and flow of female hormones, may do just that. A study of more than half a million women in the United Kingdom found that those who used hormonal contraceptives—be it…

Toddler is on a low-carb diet to control his insatiable diet

Mother, 38, puts her two-year-old son on a strict low-carb, no-sugar diet because of a genetic condition that makes him constantly hungry Kirsty Milbanhac noticed her son Reggie was ‘floppy’ when he was born in 2017 After months of tests, was diagnosed with Prader-Willi Syndrome the next year Condition causes him…

Mechanical forces control cell fate during brain formation

A new study coordinated by the Research Group in Developmental Biology at UPF shows that during the embryonic development of the brain, the cells that are between adjacent segments detect the mechanical forces generated during morphogenesis to regulate the balance between progenitor stem cells and differentiated neurons. The study has…