Discovery of cells that heal cardiac damage after infarction

Researchers at Cima and the Clinica Universidad de Navarra (Spain) have led an international study identifying the cardiac cells responsible for repairing the damage to this organ after infarction. These ‘restorative’ cells are a subpopulation of cardiac fibroblasts that play a fundamental role in the creation of the collagen scar…

Potential entry points for Huntington’s disease drug discovery

Huntington’s disease (HD) is one of the four major neurodegenerative diseases that have been most extensively studied. The clinical symptoms include uncontrolled dancing-mimicking behavior (chorea), as well as cognitive deficiency and psychiatric abnormalities. Since the biochemical activity of the mutant huntingtin protein (mHTT) that causes the disease is uncharacterized, the…