A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers. The researchers targeted their immunotherapy approach to alterations in the common cancer-related…
Researchers develop mutant gene-targeted immunotherapy approach to fight cancers
A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers. The researchers targeted their immunotherapy approach to alterations in the common cancer-related…
Deep learning-based splice-AI can help predict the onset of Alzheimer's disease
Korea Brain Research Institute (KBRI, President Suh Pann-ghill) announced that the research team led by Dr. Jae-Yeol Joo discovered new cryptic splice variants and SNVs in PLCg1 gene of AD-specific models for the first time using Splice-AI. This research outcome was published in PNAS, a world-renowned academic journal. Prediction of…
SARS-CoV-2 variants emerge during humoral immunity phase of acute COVID-19
Among the biggest challenges to containing the ongoing pandemic of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the emergence of mutations that allow the virus to evade host immune responses. Initially, changes in the SARS-CoV-2 genome were slow to emerge, due perhaps…
Genetic mechanism enables TB-causing bacterium to remember and rapidly respond to stress
Tuberculosis bacteria have evolved to remember stressful encounters and react quickly to future stress, according to a study by computational bioengineers at Rice University and infectious disease experts at Rutgers New Jersey Medical School (NJMS). Published online in the open-access journal mSystems, the research identifies a genetic mechanism that allows…
Researchers use functional test to measure the effect of inherited variants in BRCA2 cancer gene
Researchers at Mayo Clinic have combined results from a functional test measuring the effect of inherited variants in the BRCA2 breast and ovarian cancer gene with clinical information from women who received genetic testing to determine the clinical importance of many BRCA2 variants of uncertain significance (VUS). The findings were…
Genetic variants for skin color in African Americans linked to vitamin D deficiency
One day, physicians may be able to look at an African American’s skin color, and with the help of other determinants, know if prescribing vitamin D supplements would lower that person’s risk of getting cancers of the prostate, colon, rectum or breast. “We should not shy from this new study…
LifeArc supports the GenOMICC COVID-19 Study
Medical research charity, LifeArc, announces today that it is providing £5 million funding to support the work of the GenOMICC COVID-19 Study, led by the GenOMICC consortium in partnership with Genomics England. The study, launched in May 2020, is using genomics to investigate why some people are affected more severely…
Epilim IV
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. EPILIM® IV Sodium Valproate Consumer Medicine Information What is in this leaflet This leaflet answers some common questions about Epilim IV. It does not contain all of the available information. It does not take the place of…
What is Polymyalgia Rheumatica?
Polymyalgia rheumatica (PMR) is a rheumatic disease characterized by recurrent inflammatory episodes. PMR is usually seen in Caucasians living in Northern Europe and North America. The condition generally affects people over the age of 50 years (with average patient age being above 70 years), and is more common in women…
Genotropin MiniQuick
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. GENOTROPIN MINIQUICK® somatropin (rbe), recombinant human growth hormone Consumer Medicine Information What is in this leaflet This leaflet answers some of the common questions that you may have about GENOTROPIN MiniQuick. It does not contain all the…