A twin study recently completed at the University of Helsinki indicates that the machinery responsible for energy handling in fat tissue is working poorly in obesity. In the study, a clear reduction was seen in the activity of mitochondrial genes in obesity in fat tissue, while similar genome-level change in…
New Guidance on Personalized Exercise for BP Control
Recommendations for prescribing exercise to control high blood pressure have been put forward by various medical organizations and expert panels, but finding the bandwidth to craft personalized exercise training for their patients poses a challenge for clinicians. Now, European cardiology societies have issued a consensus statement that offers an algorithm…
Study details how aerobic exercise reverses degenerative process that leads to metabolic diseases
Adipose tissue is not just a simple reservoir of energy for periods of food scarcity. It contributes significantly to regulation of the metabolism, releasing various molecules into the bloodstream, including microRNAs that modulate the expression of key genes in different parts of the organism, including the liver, pancreas, and muscles….
Scientists identify metabolic features specific to the autistic brain
Skoltech scientists looked into the differences in the concentrations of multiple metabolites in healthy humans and individuals suffering from Autism Spectrum Disorder (ASD), gaining a deeper insight into the molecular processes that take place in the brain of autistic individuals. The results of the study were published in Nature’s Communications…
New yeast model of metabolic disorders may lead to life-saving therapies
There are hundreds of metabolic disorders—including phenylketonuria, tyrosinemia, maple syrup urine disease and homocystinuria. These disorders lead to congenital diseases that produce a critical enzyme deficiency that interferes with the body’s metabolism. The pathologies and symptoms vary among the diseases, but all of them are usually fatal and have no…