Vaccinations not a risk factor for multiple sclerosis

Data from over 12,000 multiple sclerosis (MS) patients formed the basis of a study by the Technical University of Munich (TUM) which investigated the population’s vaccination behavior in relation to MS. It showed that five years before their diagnosis, MS patients were statistically less likely to receive vaccinations than comparator…

Potential way to improve cancer surgery outcomes by managing nontraditional risk factors: Depression, lack of coping strategies, availability of patient’s ’emergency’ resources tied to complications

In a study of 142 patients preparing for cancer surgery, Johns Hopkins Medicine researchers say they have evidence that psychological or social risk factors such as depression, limited resilience and lack of emergency resources along with standard medical risk factors such as high blood pressure or diabetes are linked with…

Newly discovered leukodystrophy in children: Potential cure: The gene that causes the disease is called DEGS1 and its defect may be counteracted with fingolimod

The Neurometabolic Diseases research team at IDIBELL and CIBER of Rare Diseases (CIBERER), led by ICREA Professor Aurora Pujol, has uncovered a novel disease of children affecting the brain white matter -the myelin sheath-, leading to severe incapacity and death in some cases. The gene causing the disorder is called…

A boundary dance of amyloid-beta stepping into dementia: Formation mechanism of the causative substances of Alzheimer’s disease revealed by molecular dynamics simulations and NMR experiments

Many proteins aggregate at higher concentrations and form spherical substances called oligomers and acicular substances called amyloid fibrils. These protein aggregates cause more than 30 kinds of diseases, for example, Alzheimer’s disease is thought to be caused by the oligomers and amyloid fibrils formed by aggregation of amyloid-β (Aβ) peptides….