Obesity ups odds for severe COVID-19 in younger patients

It’s clear that age and chronic disease make bouts of the pandemic coronavirus more severe—and even deadly—but obesity might also put even younger people at higher risk, a pair of new studies suggest. The researchers suspect that inflammation throughout the body linked to obesity could be a powerful factor in…

Why people gain weight as they get older

Many people struggle to keep their weight in check as they get older. Now new research at Karolinska Institutet in Sweden has uncovered why that is: Lipid turnover in the fat tissue decreases during ageing and makes it easier to gain weight, even if we don’t eat more or exercise…

Certain metabolites linked to stem cell function in the intestine: Molecules called ketone bodies may improve stem cells’ ability to regenerate new intestinal tissue

MIT biologists have discovered an unexpected effect of a ketogenic, or fat-rich, diet: They showed that high levels of ketone bodies, molecules produced by the breakdown of fat, help the intestine to maintain a large pool of adult stem cells, which are crucial for keeping the intestinal lining healthy. The…

Adolescents who skip breakfast may develop obesity

A paper published in Scientific Reports describes how researchers affiliated with the University of São Paulo’s Medical School (FM-USP) in Brazil and colleagues at institutions in Europe evaluated behaviors leading to weight gain in adolescents. Childhood obesity can favor the premature emergence of health issues such as type 2 diabetes…

Early and ongoing experiences of weight stigma linked to self-directed weight shaming: New study identifies key characteristics of people who internalize weight bias

Weight bias is a common form of prejudice against people who are viewed as having excess weight. Some individuals who struggle with weight may internalize the stigma directed toward them, blaming and devaluing themselves because of their weight. While it’s known that weight “self-stigma” is associated with poor mental and…

The brain consumes half of a child’s energy — and that could matter for weight gain: New paper proposes that variation in brain energy expenditure during childhood could be linked to obesity risk

Weight gain occurs when an individual’s energy intake exceeds their energy expenditure — in other words, when calories in exceed calories out. What is less well understood is the fact that, on average, nearly half of the body’s energy is used by the brain during early childhood. In a new…

US preschoolers less pudgy in latest sign of falling obesity

Preschoolers on government food aid have grown a little less pudgy, a U.S. study found, offering fresh evidence that previous signs of declining obesity rates weren’t a fluke. Obesity rates dropped steadily to about 14% in 2016—the latest data available—from 16% in 2010, the Centers for Disease Control and Prevention…

Improved diabetes in spite of obesity

Eating too much fat and sugar causes weight gain and reduced health. But why is that, and is there a remedy? In a study published in the journal Cell, Prof. Jens Brüning’s research group at the Max Planck Institute for Metabolism Research in Cologne has shown that altering fat metabolism…