AK Treatments: Study Reviews Long-Term Efficacy Data

The four most effective treatments for long-term clearance of actinic keratosis (AK) are photodynamic therapy with aminolevulinate (ALA-PDT); imiquimod, 5%; photodynamic therapy with methyl aminolevulinate (MAL-PDT); and cryosurgery, results from a systemic review and meta-analysis suggest. To date, many studies have reported that “most interventions are superior to placebo in terms of…

Certain metabolites linked to stem cell function in the intestine: Molecules called ketone bodies may improve stem cells’ ability to regenerate new intestinal tissue

MIT biologists have discovered an unexpected effect of a ketogenic, or fat-rich, diet: They showed that high levels of ketone bodies, molecules produced by the breakdown of fat, help the intestine to maintain a large pool of adult stem cells, which are crucial for keeping the intestinal lining healthy. The…

AI reveals new breast cancer types that respond differently to treatment: Revelations could personalize treatment, including picking out those likely to benefit from immunotherapy

Scientists have used artificial intelligence to recognise patterns in breast cancer — and uncovered five new types of the disease each matched to different personalised treatments. Their study applied AI and machine learning to gene sequences and molecular data from breast tumours, to reveal crucial differences among cancers that had…

Bone cells suppress cancer metastases

In breast cancer, there are cases of women and men whose cancer returns in their bones 20-30 years after they were treated for their primary disease and thought they were cancer-free. This phenomenon always puzzled Jefferson researcher Karen Bussard, PhD. How is it possible that breast cancer cells from a…